Keeping weight off may be stymied by fat cells’ ‘memory’ of obesity

Some genetic changes in fat cells don’t go away after weight loss, a study in mice and human cells suggests.
Science and Technolgy blog
Some genetic changes in fat cells don’t go away after weight loss, a study in mice and human cells suggests.
A solitary dolphin in the Baltic Sea has been recorded talking to himself, leading researchers to wonder whether he’s lonely and calling out for friends.
Last year we reported on preliminary research suggesting that ancient Egyptians may have used hallucinogens in their religious rituals, based on the presence of a few key chemical signatures taken from a ceremonial mug. Now those researchers have extended their…
So far, all of the cargo bikes we’ve tested have been what are called “long tails,” which means the frame is extended out past the seat, moving the rear wheel back and creating a space for cargo or extra passengers.…
Decoding emergent languages in AI can have many benefits.
Ghosting, a common form of rejection in the digital era, can leave individuals feeling abandoned and confused. New research suggests that the effects may be even deeper, linking ghosting and stress to maladaptive daydreaming and vulnerable narcissism. The study was…
The senses of sight and sound are usually mingled in the brain, but not for people with aphantasia.
Researchers now think the boat was a local “føringsbåt” for passengers and cargo.
The Book of Kells is considered one of the finest surviving medieval manuscripts.
In a study published in the Journal of Applied Psychology, researchers found that occupational roles explain a significant portion of variance in personality traits, revealing distinct personality profiles across 263 different occupations. Understanding how personality traits align with specific occupations…
Monotreme (noun, “MON-oh-treem”) Monotremes are a unique group of mammals that lay eggs. Only five species of monotreme exist today. All live in either Australia or New Guinea. The platypus (Ornithorhynchus anatinus) is one example. The other four belong to…
Some tadpoles seem to have a unique way to keep their watery cribs clean: They don’t poop for weeks! These baby Eiffinger’s tree frogs live in Taiwan and on the Japanese islands of Ishigaki and Iriomote. Even as adults, they’re…
D-Wave says its new Advantage2 processor, which is designed for complex applications in AI, optimization and data science, is faster and more accurate than its existing 5,000-qubit system.
Marriage has long been associated with better health outcomes, but its effects on aging may depend on gender and relationship history. A new study of older Canadians found that married men aged more successfully than their never-married peers, but for…
Why aren’t the solstices the coldest and hottest days of the year?
A recent study conducted by scientists in France and published in Translational Psychiatry offers new insights into how depression affects the brain’s processing of positive and negative experiences. The research found that during depressive episodes, specific brain circuits become hyperactive…
Cardiovascular disease develops and presents differently in women and men. But medical guidelines are often based on studies that excluded women.
A recent study published in the American Journal of Clinical Nutrition highlights the potential benefits of eating fish during pregnancy. Researchers found that maternal fish consumption was associated with about a 20% lower likelihood of an autism spectrum disorder diagnosis…
An analysis of ancient residues left on a vase depicting the Egyptian deity Bes reveals it may have been used to reenact a myth.
A study of children with autism found that their attention to pictures of cute animals and children varies depending on the severity of their autism symptoms. Children with low-to-moderate autistic symptoms and those without autism spent more time looking at…
A recent study published in the Journal of Personality sheds light on how two distinct facets of narcissism affect the likelihood and motivations behind gift-giving. The findings reveal that individuals high in narcissistic admiration are more likely to give gifts,…
The James Webb Space Telescope and the Hubble Space Telescope recently released a chilling view of two spiral galaxies, IC 2163 and NGC 2207, merging into one.
Evo is a large language model that is not trained on words but on the genomes of millions of microbes. It can accurately predict the effects of mutations.
Data from China’s Zhurong rover has revealed what appears to be an ancient shoreline streaking through Mars’ northern hemisphere.
A long-term study has shed new light on how attention-deficit/hyperactivity disorder (ADHD) changes over time, finding that most individuals experience alternating periods of symptom remission and recurrence rather than a static course of persistent symptoms. The research, published in the…
Gray hair is often a sign of aging, but is it possible to delay its advance or reverse the color change?
New research suggests that climate change is currently driving a surge in global dengue infections and that case rates could increase by 60% by 2050.
American businesses spend close to US$100 billion each year to secure top advertising spots in search engine results – even though it’s not exactly a secret that most online shoppers scroll right past them. In fact, organic links – results…
A recent study published in Alcohol and Alcoholism reveals a surprising link between intelligence in adolescence and drinking habits later in life. Researchers found that individuals with higher IQ scores in high school were more likely to be moderate or…
A new meta-analysis found that yoga interventions improve self-reported symptoms of posttraumatic stress disorder (PTSD) immediately after the intervention. However, no improvement was observed when symptoms were assessed by a clinician. These interventions also reduced both immediate and long-term symptoms…
The second season of Silo, Apple TV’s dystopian sc-fi drama, is off to a powerful start with yesterday’s premiere. Based on the trilogy by novelist Hugh Howey, was one of the more refreshing surprises on streaming television in 2023: a…
New research published in Evolutionary Behavioral Sciences challenges a popular belief: men do not necessarily spend more on gifts for affair partners than for their committed partners. Instead, both men and women spend more on maintaining long-term relationships, with significantly…
Scientists taught rats to drive to a certain destination, but the rodents took a detour, suggesting they enjoy both the journey and the rewarding destination.
These leathery turtles spend most of their lives buried motionless in river mud, but burst into action to catch their unsuspecting prey.
Large language model AIs might seem smart on a surface level but they struggle to actually understand the real world and model it accurately, a new study finds.
A large-scale cross-cultural study published in Evolutionary Psychological Science found that people in relationships, particularly satisfying ones, report higher emotional wellbeing and life satisfaction than singles. Menelaos Apostolou and colleagues investigated whether single individuals are emotionally better off than those…
It’s Half-Life 2 week at Ars Technica! This Saturday, November 16, is the 20th anniversary of the release of Half-Life 2—a game of historical importance for the artistic medium and technology of computer games. Each day up through the 16th, we’ll be running…
Editor in chief Nancy Shute recounts the 50-year anniversary of the hominid’s discovery, which upended the study of human evolution.
Readers wondered if mayo qualifies as a non-Newtonian fluid, and X user @Lightning456243 asked how a quantum computer can identify its own errors.
The near-complete database reflects a spirit of trust and collaboration among the country’s scientific community — but will it last?
A new study has identified a specific brain pathway that could explain how positive expectations of relief reduce pain, even without actual medication. Researchers discovered a circuit connecting the anterior cingulate cortex, brainstem, and cerebellum that activates when mice expect…
From delicate dandelions to mighty oak trees, millions of plants use seeds to reproduce. But where did the first seeds come from?
Stress can shape how memories are formed, a study in mice suggests. The findings could point the way to future treatments for PTSD and anxiety.
SpaceX’s Starlink Internet satellites are responsible for more and more public reports of unexplained anomalous phenomena (UAPs), but most recent cases remain unsolved, according to a US government report released Thursday. Starlinks often move across the sky in “trains” that…
The Lafayette meteorite was discovered in a drawer at Purdue University in 1931, with no clear indication of how it got there. A new analysis of the rock reveals evidence of liquid water on Mars 742 million years ago.
Immune cells produced during severe COVID-19 infection may shrink tumors. The unexpected mechanism offers a new therapeutic possibility for advanced and treatment-resistant cancers.
According to a study published in New Media & Society, misogynistic language is pervasive within online communities of involuntarily celibate men (incels), with more than 80% of threads containing misogynistic terms. Michael Halpin and colleagues examined how members of the…
Until now, Antarctica was the only continent on Earth without any known amber fossils. But sediment cores taken from below the seafloor have revealed a tiny piece of fossilized resin holding fragments of an ancient rainforest that covered the South…
Researchers have analyzed mummified remains pulled from Siberia’s permafrost in 2020 and determined they belong to a 3-week-old saber-toothed kitten that died at least 35,000 years ago.
The budget-friendly ProForm 750R rowing machine is even better value than ever with this price cut.